On the nature of medial temporal lobe contributions to the constructive simulation of future events.

نویسندگان

  • Daniel L Schacter
  • Donna Rose Addis
چکیده

A rapidly growing number of studies indicate that imagining or simulating possible future events depends on much of the same neural machinery as does remembering past events. One especially striking finding is that the medial temporal lobe (MTL), which has long been linked to memory function, appears to be similarly engaged during future event simulation. This paper focuses on the role of two MTL regions--the hippocampus and parahippocampal cortex--in thinking about the future and building mental simulations.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Episodic future thinking in amnesic mild cognitive impairment.

Results from behavioral studies of amnesic patients and neuroimaging studies of individuals with intact memory suggest that a brain system involving direct contributions from the medial temporal lobes supports both remembering the past and imagining the future (Episodic Future Thinking). In the present study, we investigated whether amnesic Mild Cognitive Impairment (aMCI) affects EFT. Amnesic ...

متن کامل

Medial temporal lobe damage causes deficits in episodic memory and episodic future thinking not attributable to deficits in narrative construction.

The medial temporal lobe (MTL) makes critical contributions to episodic memory, but its contributions to episodic future thinking remain a matter of debate. By one view, imagining future events relies on MTL mechanisms that also support memory for past events. Alternatively, it has recently been suggested that future thinking is independent of MTL-mediated processes and can be supported by regi...

متن کامل

Constructive episodic simulation: temporal distance and detail of past and future events modulate hippocampal engagement.

Behavioral, lesion and neuroimaging evidence show striking commonalities between remembering past events and imagining future events. In a recent event-related fMRI study, we instructed participants to construct a past or future event in response to a cue. Once an event was in mind, participants made a button press, then generated details (elaboration) and rated them. The elaboration of past an...

متن کامل

Endoscopic Transsphenoidal Resection of a Medial Temporal Arachnoid Cyst in a Patient with Temporal Lobe Epilepsy

Abstract Introduction: Arachnoid cysts are developmental cystic lesions which may be found as an incidental finding on neuroimaging or present with symptoms of headache, seizure and neurologic deficit. Presentation with seizure is more common with larger sizes and temporal location. Presentation with TLE is rare, and fenestration of cysts had variable results for seizure control. Here in, we r...

متن کامل

Fluent Aphasia From Herpes Simplex Encephalitis

The present case report introduces a patient with fluent aphasia, anterograde amnesia and anosmia due to herpes simplex encephalitis after her first delivery. The left medial temporal lobe was one of the main areas involved. On aphasia testing she showed severe anomia on both confrontation and free recall, agraphia, alexia, repetition disorder and some auditory comprehension impairments. Therap...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Philosophical transactions of the Royal Society of London. Series B, Biological sciences

دوره 364 1521  شماره 

صفحات  -

تاریخ انتشار 2009